Giantcell fibroma is a type of fibroma not associated with trauma or irritation. Pdf giant cell fibroma a case report semantic scholar. Odontogenic fibroma pdf the odontogenic fibroma is a rare, object oriented systems development ali bahrami free pdf dow benign tumor of mesodermal origin, and one of the most illdefined and least. Although fibroma of tendon sheath is typically sclerotic and nodular fasciitis is typically not, there is sufficient variation in patterns to cause overlap. Dec, 2018 how can oral giant cell fibroma be prevented. Arrows highlight the stellate shaped and multinucleated fibroblasts seen in giant cell fibromas. Clinically it is presented as a painless, sessile, or pedunculated growth which is usually confused with other fibrous lesions like irritation fibromas. Acinic cell adenocarcinoma mucoepidermoid carcinoma, low grade polymorphous lowgrade adenocarcinoma monomorphic adenoma gingival cyst of adult lymphoepithelial cyst epidermoiddermoid cyst thyroglossal tract cyst squamous cell carcinoma verrucous carcinoma lymphoma metastatic carcinoma melanoma sarcoma salivary gland adenocarcinoma. The giant cell fibroma is a reactive fibrous overgrowth of the oral mucosa characterised by the presence of bizarre large stellate mononuclear and multinuclear cells in the lamina propria. Central giant cell granuloma in 1953 jaffe first described cgcg as giant cell reparative granuloma.
Giant cell fibroma is a benign oral fibrous tumor and it is typically an asymptomatic sessile or pedunculated mass that is usually less than 1 cm in diameter. The cause of this pathology has not been determined. Asymptomatic nodule on the tongue dongre a, khopkar u. The tumor is characterized by a locally aggressive behavior with no reported metastatic potential. The absence of multinucleated giant cell did not help in the differential diagnosis. The cause of oral giant cell fibroma is unknown and so are the risk factors. The topic giant cell fibroma of oral cavity you are seeking is a synonym, or alternative name, or is closely related to the medical condition oral giant cell fibroma. It presents as a sessile or pedunculated nodule, usually less than 1 cm in diameter with a flat or papillary surface.
Giant cell fibroma definition of giant cell fibroma by. Cgcg is described as a benign lesion affecting the mandible and maxilla that consists of massive fibrohistocytic proliferation with numerous heavily haemosidrin laden multinucleated giant cells. Sreejana department of pathology, dr b r ambedkar medical college. Immunohistochemical markers are required to diagnose gcf. The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma in the. Peripheral ossifying fibroma pof is a reactive gingival overgrowth which is relatively uncommon in nature. An investigation of the giant cell fibroma masters dissertation. Most such lesions on the hands are labeled fibroma of. What links here related changes upload file special pages permanent link page. The gcf was first described as a separate entity among fibrous hyperplastic soft tissue lesions by weathers and callihan in 1974. Identification of a giant cell fibroma semantic scholar. A complete surgical excision of oral giant cell fibroma. Case report giant cell tumor of the maxilla in an 8 year. Chondromyxoid fibroma with secondary aneurysmal bone cyst in.
Less common lesions include fibrous dysplasia, fibroxanthoma nonossifying fibroma, chondromyxoid fibroma, solitary bone. Giant cell fibroma is a type of fibrous tumour of the oral mucosa which. Campos and gomez5 and weathers and campbell6 suggested that the stellate and multinucleate cells of giant cell fibroma. The origin of the giant cell is still controversial.
It can occur at any age and on a mucous membrane surface. Jan 09, 2014 giant cell fibroma gcf is a rare case with unique histopathology. Giant cell fibroma a case report international journal. The patient, a 19yearold female, presented with a domeshaped lesion of normal mucosal color on the attac hed gingiva apical to tooth number 11. Case report fibrous epulis misdiagnosed for combined. Giant cell fibroma gcf is a relatively rare fibrous hyperplasic lesion. Giant cell fibroma is a type of fibrous tumour of the oral mucosa which rarely affects children under the age of 10. Its occurrence is relatively rare in paediatric patients. It was named for its characteristically large, stellateshaped, mononuclear and multinucleated giant cells.
Dermis and subcutis contains hyperchromatic spindle or stellate shaped cells in a collagenous or myxoid matrix with scattered hyperchromatic, multinucleated, floretlike giant cells. Oc giant cell rich tumours vascular tumours various lines of differentiation tumourlike lesions giant cell tumour, malignant giant cell tumour haemangioma, haemangioendothelioma, angiosarcoma ewing sarcoma, nhl of bone, myeloma, chordoma, adamantinoma solitary bone cyst, aneurysmic bone cyst, fibrous dysplasia, nonossifying fibroma. The most common site for occurrence of giant cell fibroma. It belongs to the broad category of fibrous hyperplastic lesions of the oral cavity. Giant cell fibroma of hard palate a case report pathology s. Peripheral ossifying fibroma 24 peripheral giant cell proliferation 25 traumatic eosinophilic granuloma 27 frey syndrome 29 benign masseteric hypertrophy 31 traumatic myositis ossificans 32 myositis. Some studies have suggested that peripheral giant cell granuloma is the soft tissue counterpart of central giant cell granuloma. Pdf giant cell fibromas gcf of the oral cavity are found predominantly in caucasians and rarely in other races. The giant cell fibroma gcf is an interesting non neoplastic lesion of the oral mucosa. Reactive lesions and neoplasms comprise the spectrum of local. Giant cell fibroma is a type of fibroma not associated with trauma or irritation. Giant cell fibroma retrocuspic papilla retrocuspid papilla is a giant cell fibroma that occurs on the gingiva lingual to mandibular cuspids canines.
It originates from periosteum or from periodontal membrane as a response to local irritation or chronic trauma. Jan 06, 2011 asymptomatic nodule on the tongue atul dongre 1, uday khopkar 2 1 department of dermatology, government medical college, aurangabad, maharashtra, india 2 department of dermatology, seth g s medical college and kem hospital, parel, mumbai, maharashtra, india. The tumor site could include the tongue, palate, or gums. The giant cell fibroma gcf is a lesion of fibrous connective tissue origin. Traumatic fibroma, giant cell fibroma, oral benign tumor. It is often mistaken with fibroma and papilloma due to its clinical resemblance. Discussion v, we believe that the giantcell fibroma is a distinctive lesion whose charac teristic location, age distribution, sex incidence, and histologie features clearly separate it from the usual fibroma. The most common oral locations are on the gingiva of the mandible, tongue, and palate. What are the clinical features of giant cell fibroma.
Giant cell fibromas gcf of the oral cavity are found predominantly in caucasians. The giant cell fibroma is a fibrous tumour with distinct clinicopathologic features which sets it apart from the. Back of thigh, inguinal region and chest wall are the most common sites of involvement. Angelopoulou 2 1department of oral medicine and pathology, dental school, university of athens, greece. Clinicopathologic study of a series of giant cell fibroma. Fibroma of the tendon sheath fts is a benign lesion or a tumorlike reactive lesion arising from the synovium of the tendon sheath. May 31, 2018 the clinical differential diagnosis of a fibroma depends on its clinical presentation and location and includes giant cell fibroma, neurofibroma, peripheral giant cell granuloma, schwannoma, granular cell tumor, mucocele, and benign and malignant salivary gland tumors eg, see salivary gland neoplasms. Differential diagnosis fibroma of tendon sheath surgical. Microscopically similar to the giant cell fibroma, the retrocuspid papilla.
The giant cell fibroma is a benign nonneoplastic fibrous tumor of the oral mucosa. All lesions had been treated by total surgical excision. Most such lesions on the hands are labeled fibroma of tendon sheath. Giant cell fibroma of the buccal mucosa with laser excision. A case report and update of giant cell fibroma dergipark. It is painless, often has lobules nodules on its surface. Clinicopathological study of oral giant cell fibromas. Giant cell fibroma may mimic fibroma of the gingiva, but have distinctive histopathological difference. Giant cell fibroma gcf was described as a new entity of fibrous hyperplastic. Giant cell fibroma gcf is a rare case with unique histopathology. Pofs comprises of, one or more mineralized tissues, including bone, cementum like material or dystrophic calcification, within a matrix of cellular fibroblastic tissue 2. The giant cell fibroma is a benign, fibrous tumor with multiple large fibroblasts, not associated with trauma or chronic irritation. The purpose of this paper was to contribute two clinically and histologically.
Giant cell fibroblastoma is a rare fibroblastic tumor occurring mainly in young patients. Other common precursor lesions include osteoblastoma, angioma, and chondroblastoma. Identification of a giant cell fibroma sherri m lukes, joleen kuhnert and mark a mangels sherri lukes, rdh, ms, is an assistant pr ofessor in the dental hygiene pr ogram at southern illinois univer sity at carbondale, where. Printable fibroma of tendon sheath surgical pathology. Materials and methods the study group consisted of 24 cases of gcf re trieved from the files of the department of oral pathology and oral diagnosis, national taiwan university hospital, taipei, from 1987 to 2008. Giantcell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on. The patient came with a recurrent lesion after 6 months. Apr 10, 20 fibroma and giantcell tumor of tendon sheath. This report presents a series of cases of mucocele and fibroma treated by surgical excision or enucleation and the respective followup routine in the dental clinic and discusses the features to be considered in order to distinguish these lesions from each other. Demographic and clinical data of 24 cases of giant cell fibroma case sex age yr location size mm clinical diagnosis 1 f 10 tongue, left lateral border 4.
An external file that holds a picture, illustration, etc. You have discussed your clinical impression with the patient. Case report irritational fibroma of lower labial mucosa. Dermis and subcutis contains hyperchromatic spindle or stellate shaped cells in a collagenous or myxoid matrix with scattered hyperchromatic, multinucleated, floretlike giant cells with prominent nucleoli, similar to those in pleomorphic lipomas ectatic pseudovascular spaces are lined by a discontinuous row. Aneurysmal bone cyst 75% patients are under 20 years. Dermis and subcutis contains hyperchromatic spindle or stellate shaped cells in a collagenous or myxoid matrix with scattered hyperchromatic, multinucleated, floretlike giant cells with prominent nucleoli, similar to those in pleomorphic lipomas. It occurs in the first three decades of life in the mandibular gingiva, predominantly, showing predilection for females.
Oral giant cell fibroma is usually present as a mass in the mouth. Clinical features peripheral giant cell granuloma can be seen in individuals over a wide age range. It was first described by weathers and callihan in 1974. Outcomesresolutions the prognosis of oral giant cell fibroma is excellent on its complete surgical removal. Oral giant cell fibroma j formos med assoc 2009 vol 108 no 9 727 table. Case report giant cell tumor of the maxilla in an 8 year old boy. A giant cell fibroma, a type of fibrous hyperplasia, was discovered during a preventive patient visit in the dental hygiene clinic at a midwestern university. The giant cell fibroma is a fibrous tumour with distinct clinicopathologic features which sets it apart from the conventional fibroma. Peripheral giant cell granuloma is the most common jaw located giant cell lesion. It most commonly occurs on the gums, more commonly on the lower than upper. There are no significant complications due to the tumor. Pdf benign gingival overgrowths are not uncommon in the oral cavity.
The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma. A 53yearold man presented in 2009 with a tumor over the dorsum of his hand and wrist. Giant cell fibroma is a small usually less than 5mm diameter firm lump in the mouth, often with a folded or pebbly surface. Oral giant cell fibroma or oral gcf is a common, benign, slowgrowing tumor of the mouth. The giant cell fibroma is a reactive fibrous overgrowth of the oral mucosa characterised by the presence of bizarre. A complete surgical excision of oral giant cell fibroma usually results in a cure. Herein, we report a case of an 8yearold chinese boy with no prior trauma in which a fts was inadvertently found in the in. Clinically it usually manifests as a small, may have be sessilepeduncalate lesion. The most common oral locations are on the gingiva of the mandible. J formos med assoc 2009 vol 108 no 9 725 original article giant cell fibroma gcf is a benign oral fibrous tumor that was described initially by weathers and callihan. What is the following step you should recommend to your patient.
The clinical differential diagnosis of a fibroma depends on its clinical presentation and location and includes giant cell fibroma, neurofibroma, peripheral giant cell granuloma, schwannoma, granular cell. Note both stellate cells and multinucleated giant cells of the giantcell fibroma. Here we are presenting a case where a sevenyearold male patient reported with a painless nodular growth in. Fts usually occurs in the upper extremities, but rarely in the knee joint. Giant cell fibroma gcf is a distinct type of fibroma with characteristic large, stellate mononuclear or multinucleated giant fibroblasts. Only its peculiar histopathological features help us to distinguish it from them. The giant cell fibroma is a localized reactive proliferation of fibrous tissue, much like the irritation fibroma. This article describes a case of giant cell fibroma in a 3yearold boy, which is an uncommon age for this lesion. Select the citation format ris, bibtex or plain text from the list below. It may be on a small stalk pedunculated or domeshaped like a limpet.
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